Jonas Salk (1914–1995): A vaccine against polio

Hormesis and the salk polio vaccine.

The production of the Salk vaccine polio virus by monkey kidney cells was generated using the synthetic tissue culture medium, Mixture 199. In this paper's retrospective assessment of this process, it was discovered that Mixture 199 was modified by the addition of ethanol to optimize animal cell survival based on experimentation that revealed a hormetic-like biphasic response relationship. This...

The 1954 Salk poliomyelitis vaccine field trial.

Portrait

Born in 1944, I grew up in a world in which polio was both a gripping fear and real threat. Then in a matter of a few years-polio was eradicated by a vaccine developed by Jonas Salk. Later I learned that Salk's efforts were built on pioneering work of many others, including John Enders, Thomas Weller and Frederick Robbins (Nobelists, 1954), and David Bodian, who pioneered studies of polio patho...

Patenting the Sun. Polio and the Salk Vaccine. Jane S. Smith. Morrow, New York, 1990. 413 pp. + plates. $22.95.

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2 0 0 5 Young Scientists Follow in Footsteps of Jonas Salk

Young Scientists Follow in Footsteps of Jonas Salk Two developing medical scientists — one from York College, the other from Hunter — recently completed internships that will surely be high points of their promising careers. Fiona Smith, a 2005 graduate of Yo r k C o l l e g e, and Irina Chaikhoutdinov, an ’05 g raduate of the Honors College at Hunter C o l l e g e, worked this past summer at o...